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Indications: Treatment resistant hypertension Most often used as a supplemental drug that is added on to a daily treatment regimen for patients with hypertension that is not adequately controlled by a combination of lifestyle modification, thiazide diuretic, plus an ACE inhibitor or Angiotensin receptor blocker (Brook & Townsend, 2026)

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After the infusion, most people can return to their daily activities without downtime

Acute kidney injury due to volume depletion has been reported in postmarketing reports occurring in patients who experienced nausea, vomiting, or diarrhea, leading to dehydration